Pulmonary ionocyte
Web这两个课题组均通过单细胞RNA测序技术在人和鼠的呼吸道上皮细胞中发现了一种新型肺细胞——“ 肺部离子细胞 ” (pulmonary ionocyte)，这种新型肺细胞共表达FOXI1以及H+分泌的V … WebMien profiling on 75,000 single single creates a comprehensive cell atlas of the human lung that includes 41 out of 45 previously known cell species and 14 new ones.
Pulmonary ionocyte
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WebAug 1, 2024 · A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte. Nature. DOI: 10.1038/s41586-018-0394-6 The Harvard Gazette (2024). Cystic … WebNov 21, 2024 · Mucus secretion and mucociliary transport are essential defense mechanisms of the airways. Deviations in mucus composition and secretion can impede mucociliary transport and elicit airway obstruction. As such, mucus abnormalities are hallmark features of many respiratory diseases, including asthma, cystic fibrosis and …
The major function of the lungs is gas exchange between the lungs and the blood. The alveolar and pulmonary capillary gases equilibrate across the thin blood–air barrier. This thin membrane (about 0.5 –2 μm thick) is folded into about 300 million alveoli, providing an extremely large surface area (estimates varying between 70 and 145 m ) for gas exchange to occur. The lungs are not capable of expanding to breathe on their own, and will only do so when there is … WebFeb 27, 2024 · the possible regulation of these pulmonary ionocyte-related factors in the yak lung for adaptation to high-altitude hypoxia. The localization and expression of CTFR, …
WebAug 1, 2024 · They also described several new cell types, including one that the team has named the pulmonary ionocyte, after salt-regulating cells in fish and amphibian skin. These lung cells express similar genes as fish and amphibian ionocytes, the team found, including a gene coding for the transcription factor Foxi1, which regulates genes that play a role in … WebAug 1, 2024 · When the cystic fibrosis gene from 1989, dubbed CFTR, is active, it is usually in the pulmonary ionocyte, which makes up just one-to-two percent of the airway. The team reported this discovery ...
WebSep 2, 2024 · Discoveries from both of teams, point to new strategies for treating cystic fibrosis, such as increasing the amount of pulmonary ionocytes to increase the amount of …
WebAug 1, 2024 · By associating cell-type-specific expression programs with key disease genes, we establish a new cellular narrative for airways disease.Single-cell RNA sequencing … kevin massey philadelphia inmateWebAug 3, 2024 · 研究人员将它们命名为“肺离子细胞（ pulmonary ionocyte ）”，因为它们的基因表达模式有点类似离子细胞，过去，这类细胞被认为是专门负责调节鱼类腮和蛙类皮肤中离子迁移和水合作用的。. 令人意外的是，小鼠和人类组织中这类细胞表达的CFTR基因比其他任 … kevinmasoudmofidi first investmenthttp://www.ebiotrade.com/newsf/2024-8/202482164111706.htm kevin mason port townsendWebpulmonary ionocyte : a possible key to cystic fibrosis Proinfinityclasses.com August 29, 2024 Cystic Fibrosis is a progressive, genetic disease that causes persistent lung infections and limits the ability of a person to breathe over a time. kevin massage therapistWeb8月1日，《Nature》连发两篇文章，同时揭示了一种新型肺细胞——“肺部离子细胞”（pulmonary ionocyte）。两个不同的研究团队利用单细胞RNA测序技术对人类以及小鼠的呼吸道细胞绘制了详细的分子图谱，从中发现了新的知识点。 kevin massey facebookWebWe identify a rare cell type, the Foxi1+ pulmonary ionocyte; functional variations in club cells based on their location; a distinct cell type in high turnover squamous epithelial structures that we term ‘hillocks’; and disease-relevant subsets of … is jaw a muscleWebAug 3, 2024 · Scientists have discovered a new type of cell in the human respiratory tract called the pulmonary ionocyte, and linked it to lung function decline in cystic fibrosis. … is jaw a interjection